vrijdag, juli 26, 2013

guinea pigs on vaccine research and nutritional experiments






24-7-2013
By Jorge Barrera
APTN National News

 The nutritional experiments conducted in First Nation communities and in Indian residential schools were not the only example where Canada’s Indigenous population faced treatment as “guinea pigs,” academic research shows.

First Nation infants were used for Saskatchewan trials of a tuberculosis vaccine that was mired in controversy at the time of the experiment in the 1930s and 1940s.
The subject of nutritional experiments exploded last week after reports surfaced on a study by University of Guelph food historian Ian Mosby. The study found that experiments were conducted in six residential schools and communities in northern Ontario, northern Manitoba, British Columbia, Alberta and Nova Scotia between 1942 and 1952.

Previous and ongoing academic research shows, however, that the nutritional experiments were part of a wider pattern in the medical and scientific community’s approach to Indigenous people at the time which included experimentation and the persistence of certain types of surgeries that were no longer conducted on non-Indigenous people.

Academic research also shows that many Indigenous people who died undergoing medical care for diseases like tuberculosis (TB) were buried in unmarked graves because Indian Affairs would not pay to take their bodies back to their home communities.

“Historians have been reluctant to question medical care because we are enthralled with the power of medicine,” said Brock University professor Maureen Lux, who published a paper on the vaccine trials in 1998 and is currently working on a book that delves into the still thinly-explored realm of the treatment of Indigenous people in sanatoriums. “Once I started looking at what was going and how they were operated and in whose interest, it becomes a fairly dark story.”

The vaccine trial on First Nation children from the Qu’Appelle reserves in southern Saskatchewan is one of those threads in that story.

The bacille Calmette-Guerin (BCG) vaccine trials were backed by the National Research Council and Indian Affairs. While the trials were eventually successful and the vaccine is still around today, one of the doctors involved with the experiment at the time worried about the dangers and believed Ottawa could find itself on the hook if something went wrong.

It was already apparent to medical officials before the trials that TB rates were dramatically lowered by improving the living conditions of First Nation people living on reserve, according the study written by Lux titled, Perfect Subjects: Race Tuberculosis and the Qu’Appelle BCG Vaccine Trial.

Between 1930 and 1932, the tuberculosis rate had been cut in half after a federally-backed Qu’Appelle Demonstration Health Unit began focusing on changing the situation on the ground. It replaced one-room log huts with frame houses, drilled wells to improve water supply, provided families with hens and seed and improved the food given to school children and pregnant women, according to Lux’s study. A nurse was also hired to give care to children suffering from infections disease in their own home.

“The general death rate and the infant mortality rate both also fell. Thus, before the BCG vaccine trials were begun, the tuberculosis death rate had been reduced by half by marginal improvements in living conditions, and especially by segregating those with active tuberculosis,” wrote Lux.

But vaccines were cheaper than paying to improve the conditions of Indian residential schools and reserves or treating people in sanatoriums which could turn into lengthy stays.

Lux said the urgency to conduct the vaccine trials on First Nation infants in southern Saskatchewan was also driven by a fear that Indigenous people would infect the non-Indigenous population with TB.

“The general death rate and the infant mortality rate both also fell. Thus, before the BCG vaccine trials were begun, the tuberculosis death rate had been reduced by half by marginal improvements in living conditions, and especially by segregating those with active tuberculosis,” wrote Lux.

But vaccines were cheaper than paying to improve the conditions of Indian residential schools and reserves or treating people in sanatoriums which could turn into lengthy stays.

Lux said the urgency to conduct the vaccine trials on First Nation infants in southern Saskatchewan was also driven by a fear that Indigenous people would infect the non-Indigenous population with TB.

“They were seen as vectors of disease because TB rates in the non-Aboriginal community were falling quickly. They were better fed and housed, but not so on-reserve,” said Lux, in an interview. “My point in the article was that TB wasn’t the big threat…the big threat was poverty because more kids died of poverty related diseases than from TB.”

The BCG vaccine at the time was controversial.

A German experiment in 1930 led to the deaths 71 children after they were given a contaminated strain. At the time of the Qu’Appelle trial, close to 400,000 children had been vaccinated and trials had been conducted in Montreal, but it was still unclear at the time whether the vaccine would regain its virulence. The United States and Britain did not use the BCG vaccine at the time “because of fears that the vaccine was not stable,” wrote Lux.

Worries over the vaccine were expressed in a confidential memo to federal authorities.

“I feel as though it would be unwise to initiate human experimental work among Indian children who are the direct wards of the government, and for which reasons they are not in a position to exercise voluntary cooperation,” wrote Dr. R. George Ferguson, the medical superintendant of the Fort Qu’Appelle Sanatorium, to the president of the National Research Council. “Furthermore in case of difficulties arising, the government itself could not be without responsibility.”

The trial went ahead in 1933 and it proved successful. According to Lux, between 1933 and 1945, 306 infants were vaccinated and 303 were used as a control group. Only six vaccinated infants contracted TB and two died. In the unvaccinated group, 29 caught TB and nine died.

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